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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAICS
All Species:
44.55
Human Site:
S301
Identified Species:
81.67
UniProt:
P22234
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22234
NP_001072992.1
425
47079
S301
P
C
E
L
R
V
T
S
A
H
K
G
P
D
E
Chimpanzee
Pan troglodytes
XP_001140521
451
49634
S327
P
C
E
L
R
V
T
S
A
H
K
G
P
D
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532381
425
46974
S301
P
C
E
L
R
V
T
S
A
H
K
G
P
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCL9
425
47052
S301
P
C
E
L
R
V
T
S
A
H
K
G
P
D
E
Rat
Rattus norvegicus
P51583
425
47078
S301
P
C
E
L
R
V
T
S
A
H
K
G
P
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516499
348
38076
R230
V
T
V
S
K
V
P
R
S
G
S
M
S
N
L
Chicken
Gallus gallus
P38024
426
47222
S302
P
C
E
L
R
V
T
S
A
H
K
G
P
D
E
Frog
Xenopus laevis
NP_001080163
425
47148
S301
P
C
E
L
R
V
T
S
A
H
K
G
P
D
E
Zebra Danio
Brachydanio rerio
NP_955831
425
47059
S301
P
C
H
L
R
V
N
S
A
H
K
G
P
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9I7S8
429
47263
S304
N
V
E
L
R
V
S
S
A
H
K
G
P
E
E
Honey Bee
Apis mellifera
XP_624351
420
47251
S296
K
V
Q
F
R
V
C
S
A
H
K
G
T
Q
E
Nematode Worm
Caenorhab. elegans
Q10457
423
46959
S304
E
T
T
L
K
V
S
S
A
H
K
T
T
S
D
Sea Urchin
Strong. purpuratus
XP_780342
419
46499
S295
H
C
D
L
R
V
T
S
A
H
K
G
T
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.1
N.A.
96.4
N.A.
95
96.2
N.A.
61.6
85.6
81.4
78.3
N.A.
58.7
54.5
49.6
62.1
Protein Similarity:
100
94
N.A.
98.3
N.A.
99.5
99
N.A.
69.6
92.4
90.3
91.7
N.A.
73.6
70.8
68.2
76
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
6.6
100
100
86.6
N.A.
73.3
53.3
40
80
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
26.6
100
100
86.6
N.A.
86.6
60
60
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
93
0
0
0
0
0
0
% A
% Cys:
0
70
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
70
8
% D
% Glu:
8
0
62
0
0
0
0
0
0
0
0
0
0
8
85
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
85
0
0
0
% G
% His:
8
0
8
0
0
0
0
0
0
93
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
16
0
0
0
0
0
93
0
0
0
0
% K
% Leu:
0
0
0
85
0
0
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% N
% Pro:
62
0
0
0
0
0
8
0
0
0
0
0
70
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
85
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
0
0
16
93
8
0
8
0
8
8
0
% S
% Thr:
0
16
8
0
0
0
62
0
0
0
0
8
24
0
0
% T
% Val:
8
16
8
0
0
100
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _